pentobarbital will lower the extent or outcome of alfentanil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unidentified.
Phenytoin and barbiturate blood stages need to be monitored additional frequently if offered concurrently; outcome of barbiturates on phenytoin metabolism reported for being variable; sodium valproate and valproic acid appear to reduce barbiturate metabolism; keep an eye on barbiturate blood concentrations and make acceptable dosage changes as needed
pentobarbital will minimize the level or influence of cariprazine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lower the extent or impact of quinidine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lower the level or effect of donepezil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unknown.
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pentobarbital will decrease the level or outcome of etravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will lower the extent or result of tolterodine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
Barbiturates could potentially cause fetal hurt when administered to some Expecting girl; retrospective, scenario-controlled scientific tests have instructed a connection concerning maternal intake of barbiturates and a greater-than-envisioned incidence of fetal abnormalities
pentobarbital increases effects of ifosfamide by impacting hepatic enzyme CYP2B6 metabolism. Use Warning/Keep track of. Coadministration of ifosfamide with CYP2B6 inducers may well boost metabolism of ifosfamide to its metabolite. Keep an eye on for amplified effects/toxicities if combined with CYP2B6 inducers.
pentobarbital will lessen the extent or impact of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will lower the read more extent or effect of bazedoxifene/conjugated estrogens by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Monitor Intently (one)pentobarbital will lower the level or effect of mifepristone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. CYP3A4 inducers haven't been examined, coadministration not encouraged by maker
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